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The enrollment was limited to persons with Parkinson's disease who were on dopaminergic Parkinsons medications

Wilcox previously offered compounded GLP-1s through his practice, when it was removed from the FDA shortage list he stopped providing the drug

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With an absolute oral bioavailability of approximately 79%, a terminal half-life of 25 to 68 hours supporting once-daily dosing, and no clinically meaningful food effect on absorption, orforglipron achieves what oral semaglutide could not: reliable drug exposure through a convenient dosing regimen that places no restrictions on when or how patients take their medication

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