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glp 1 not suppressing appetite anymore GLP-1 helps you feel full. But high insulin can shut it down. That means weaker signals, bigger spikes, and more hunger. More insulin → less GLP-1 → repeat. To watch the full Why GLP-1 Isn't Working: Common
Description
Animal studies have shown thyroid C-cell tumours with some GLP-1 receptor agonists, though the relevance to humans is uncertain
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Research presented at the ACR Convergence 2025 conference showed that RA patients with elevated BMI who took GLP-1 receptor agonists experienced superior improvements in disease activity scores, pain levels, and weight loss compared to controls
In Phase 1 and 2a clinical trials, once-daily subcutaneous injections of RG7697 (0.252.5 mg) for 14 days in 56 patients with T2DM and 1.8 mg of RG7697 for 12 weeks in patients with T2DM who were poorly responsive to metformin reduced body weight and improved glycemic control

Still, food sensitivities can be challenging to pinpoint
They didn't get the support to help them learn how to live in a way [00:58:00] that supports their body best