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They work by directly mimicking GLP-1 hormone activity at pharmacological concentrations, are approved by regulatory agencies for specific indications, and require both a prescription and medical supervision

Efficacy of Semaglutide in Treating Obesity: A Systematic Review of Randomized Controlled Trials (RCTs)

[1] Suspected side effects should be reported via the MHRA Yellow Card scheme

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The results are in comparison to placebo groups, demonstrating how much the drug assists lifestyle interventions alone
