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According to FDA prescribing information and pivotal clinical trials, gastrointestinal adverse effects are the most common side effects associated with tirzepatide therapy

Open communication between the patient and provider ensures that both the benefits and potential side effects are carefully weighed

Gastrointestinal side effects tend to be worst early on or after a dose increase and frequently ease as your body adjusts over several weeks

These findings may help provide context for why your response on .25 mg semaglutide might differ from othersthough genetic predisposition alone does not predict exact medication response

Telogen effluvium, the likely underlying cause, is generally self-limiting and affects a proportion of individuals undergoing rapid weight reduction, regardless of the method (whether pharmacological, surgical, or dietary)