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The clinical term anhedonia refers to the loss of pleasure in activities that used to bring you joy

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Initial evidence indicates that GLP-1 RAs may have an impact on reward circuits to nicotine dependence but needs well-powered randomized controlled trials to determine this and assess clinical application []

Method The PubMed (MEDLINE), EMBASE, Cochrane Library, and ClinicalTrials.gov databases were searched from the establishment of the database to December 24, 2022