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They found that rats who supplemented with GSE were largely protected from liver damage, thanks to GSE-derived proanthocyanidins' ability to downregulate enzymes that lead to hepatic lipotoxicity

In this issue, were diving deeper into the potential benefits of GLP-1 agonist medicationswidely known for treating diabetes and weight managementon neurological, cardiovascular, and immune system health

Studies performed primarily with -cell lines or mouse -cells demonstrate cAMP-independent actions of GLP-1R agonists to counteract endoplasmic reticulum stress 108 and to signal via the GLP-1R through -arrestin 109,110 and epidermal growth factor (EGF) receptor trans-activation 111 in order to downregulate the activities of proapoptotic protein BAD, 112 the SirT1 deacetylase, 113 and transcription factor FoxO1

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