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In the GLP-1 vs DPP-4 inhibitor cohort (2009-2022), we identified 108,322 new users of GLP-1 RAs and 55,411 new users of DPP-4 inhibitors using the National Prescription Registry

Animal studies show that GLP-1 agonists dampen HPA axis overactivity and reduce stress-induced weight gain

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For women in midlife, the better question is whether the provider can support the full picture: weight, muscle, symptoms, side effects, refills, hormones, and long-term maintenance