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A new oral version of Wegovy has been FDA-approved, offering a more affordable and accessible option to injectable GLP-1 medications that have transformed weight loss treatment for millions.

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Results: The 90% confidence intervals were 93.11%–107.22% for Cmax, 93.76%–112.65% for AUC0–t, and 91.48%–104.47% for AUC0–∞, meeting bioequivalence criteria for all primary parameters

Key findings: 29% reduction in coronary heart disease death, myocardial infarction, or ischemic stroke (3-point MACE) 21% reduction in broader cardiovascular events including revascularization (4-point MACE) Median LDL-C reduced to 45 mg/dL versus 106 mg/dL with placebo Benefits were consistent regardless of concomitant GLP-1 receptor agonist or SGLT2 inhibitor use

Attorney for the Western District of Louisiana Brandon Brown announced his resignation on January 8.