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Jastreboff, AM, Aronne, LJ, Ahmad, NN, et al

Study selection was guided by conceptual relevance and methodological quality, aiming to provide a balanced and clinically meaningful synthesis of the available evidence

Reduced food intake means less water from food (which normally contributes 20% of daily fluid intake)

Frontiers in Endocrinology , 12

Starting semaglutide first and allowing 46 weeks of tolerability before introducing bupropion is the safest approach
