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Lillys retatrutide (triple agonist targeting GLP1, GIP and glucagon) promises to be the most potent of all

[2] [3] GLP-1 medications reduced major adverse cardiovascular events by 20% in the SELECT trial, with benefits extending beyond weight loss alone

One study found that 45 percent of the weight people lost on semaglutide came from lean muscle mass

Mild nausea, stomach upset, constipation, or fatigue can occur, especially early on

doi: 10.3390/nu5062062, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 40
