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The FDA has approved these agents based on their ability to improve glycemic control, with select agents at specific doses approved for weight management

Besides its popularity for weight loss, berberine is also being studied for its effect on diabetes and heart disease risk factors

It remains unclear, however, whether such effects mitigate hypoxia risk and ultimately fibrosis and nephron loss as described below

Animal studies suggest that semaglutide could cause birth defects, but human data is limited

Dietary protein is likely being used for energy