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First, one of the key strengths of our meta-analysis was the comprehensive assessment of the effects of semaglutide on a broad spectrum of outcomes, including arrhythmic, major CV, and microvascular outcomes

Acknowledgements We thank Beat Lutz for the GAD65 cDNA, Margaret Morris for critically reading the manuscript, and Claudia Klugmann for technical assistance

The action of GLP-1 supports healthy eating behaviors and can significantly influence weight management

The main difference lies in how Tirzepatide targets two metabolic receptors instead of just one

The drugs established benefits include improvements in major adverse cardiovascular events in high-risk patients in large clinical trials, rather than signals of increased clot risk