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The dose in milligrams never changes with vial size a 2.5 mg dose is 2.5 mg whether it comes from a 5 mg or a 30 mg vial but the number of units you draw changes dramatically, because a more concentrated solution packs the same milligrams into far less liquid

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Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the STEP 4 randomized clinical trial
Figures represent outcomes at the study endpoint