how does your body make glp 1 GLP-1 Science Page GLP-1 medications are changing lives.

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Feed Your Gut Fiber-rich Carbohydrates Your gut health plays a critical role in GLP-1 secretion, especially in the colon, where fermentation of undigested carbohydrates produces substances called short-chain fatty acids (SCFAs), like butyrate, propionate and acetate

In the Phase 3 ATTAIN-1 trial, adults with obesity taking the highest approved dose achieved an average weight loss of 12.4% at 72 weeks compared with approximately 0.9% with placebo

Most patients see gradual, consistent progress

The pivotal STEP trials for semaglutide and SURMOUNT trials for tirzepatide included thousands of participants with monitoring for suicidal ideation using standardized tools such as the Columbia-Suicide Severity Rating Scale (C-SSRS), and did not demonstrate elevated rates compared to placebo groups