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Brain Signaling : GLP-1 receptors are abundant in the hypothalamus and brainstem areas that control hunger

DOI: 10.1056/NEJMoa2301972 Doggrell SA

Ultimately, genediseasedrug models, supported by integrative resources like GeneDive and other PGx knowledge bases, can drive precision prescribing of dual GIP/GLP-1 agonists, matching patients to the greatest achievable metabolic and cardiovascular advantage [86]

This notion is supported by the observation that Hp infection, which negatively influenced plasma ghrelin dynamics, was shown to correlate in a positive manner with the BMI of Hp infected patients (57)
