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The efficacy and safety of berberine in combination with cinnamon supplementation in patients with type 2 diabetes: a randomized clinical trial

Christensen M, Knop FK, Holst JJ, et al

Orforglipron is the active ingredient
That is why a provider-guided process matters

OTC products may contain ingredients that support weight loss through different pathways, but they do not activate the GLP-1 receptor itself