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Do not take within a few hours of bedtime.

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Gudbergsen H, Overgaard A, Henriksen M, Whrens EE, Bliddal H, Christensen R, et al

doi: 10.1152/japplphysiol.00845.2009

The troubleshooting mindset you used during treatment applies here too

Notes: Leftovers - Refrigerate in an airtight container for up to three days