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The medication is typically injected in the abdomen, thigh, or upper arm, with rotation of injection sites recommended to prevent skin irritation

Part of why there is a lower risk of death and more favorable cardiovascular outcomes is because, beyond weight reduction, semaglutide alleviates heart failure symptoms and reduces the risk of heart attack and stroke in individuals with obesity

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Tomlinson DJ, Erskine RM, Morse CI, Winwood K, Onambl-Pearson G

RCTs are typically not powered for psychiatric endpoints and often enroll highly selected, lowerrisk populations