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Stage 1 includes individuals with higher risk of developing dysglycaemia (defined based on validated country-specific risk scores than those with stage 0 or normal -cell function, whose high insulin resistance would be compensated by increased insulin production and glucose remains near normal despite gradual minimal decline in -cell function or mass
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As a result, additional parameters indicative of weight loss efficacy were not included within the scope of this investigation

[DOI] [PubMed] [Google Scholar] 77.Xu X., Lin L., Chen P., Yu Y., Chen S., Chen X., Shao Z

Doing so carries significant safety risks, including exposure to counterfeit or unregulated substances, unknown drug interactions, and the absence of appropriate medical supervision
