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Women using oral hormonal contraceptives should be aware that Zepbound may reduce their effectiveness, requiring alternative or backup contraception during initiation and dose escalation periods

Although not FDA-approved for non-diabetic use, many studies have shown semaglutide's effectiveness in non-diabetics seeking weight loss

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This is because clinical trials have not been long enough to assess pancreatic cancer risk, and the risk may still be present

This work was supported by the National Natural Science Foundation of China (NSFC No