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It is the first in a new class of drugs called DPP-4 inhibitors, which aim to reduce the amount of fat released into the bloodstream
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Interestingly, some trial participants reported improved sleep quality on retatrutide, possibly related to weight loss reducing sleep apnea symptoms

The case series in Medicine specifically highlighted this mechanism, noting that the body water loss associated with GLP-1 agonists may be more significant than commonly appreciated
