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The OASIS 1 and 2 trials compared the therapeutic efficacy and clinical safety profile of once-daily oral semaglutide 50 mg versus placebo on overweight and obese participants without T2DM and both with and withoutT2DM, respectively

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New study result Tirzepatide vs semaglutide SURMOUNT 5 RCT Total body weight loss: 20.2% with tirzepatide 13.7% with semaglutide Discontinuations due to gastrointestinal events: tirzepatide 2.7%, semaglutide 5.6% vomiting tirzepatide 15.0% vs semaglutide 21.3%

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