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Get a baseline thyroid panel before starting tirzepatide, then recheck TSH and free T4 at 6 to 8 weeks

Many researchers find their optimal dose between 7.5 mg and 10 mg

2020 How to use Trulicity Injection 1.5 mg Pre filled Pen^ Inject subcutaneously in the abdomen, thigh, or upper arm

This is fundamentally different from something like semaglutide , which has a similar half-life but different peak timing characteristics, or short-acting peptides where injection timing is critical
