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Due to the limit of available articles at the time of search, the initial search was quite broad with a very narrow final evidence base which mainly resulted in case reports or case series, narrative scoping reviews, or small retrospective cohorts

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This study enrolled adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

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Month 23 Dose Escalation Dose increases on a structured schedule based on tolerability and response

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