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GLP-1RAs also reduce food intake by modulating appetite-regulating pathways in the brain, resulting in weight loss (Koide et al., 2025) (see Figure 1)

PMID 38629387

2023, NEJM) showed 20 percent MACE reduction

So I had a practitioner, a naturopath, tell me the other day that she had a patient who went on this and had a really significant issue and ended up in the hospital, and she said none of her all of her practitioners dismissed that

Weight management in type 2 diabetes For type 2 diabetes patients who are overweight or obese (which describes the majority), GLP-1 medications address both the glycemic and the weight components of their disease