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GLP-1 RAs, Alcohol Use disorders and Reward-Seeking Behaviors New research in JAMA Psychiatry shows that semaglutide, a GLP-1 receptor agonist, reduced alcohol consumption in adults with alcohol use disorder

Tirzepatide can influence muscle composition during weight loss, but the risk depends on individual factors including baseline metabolism, protein intake, and exercise patterns

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Switching to the oral small molecule glucagon-like peptide-1 (GLP-1) orforglipron after taking injectable GLP-1s helped patients maintain mostbut not allof their weight loss, according to a clinical trial led by Weill Cornell Medicine and NewYork-Presbyterian investigators.