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New agents being considered for the treatment of obesity are analogs of the peripheral peptide hormones, like glucagon-like peptide-1 (GLP-1), peptide YY, and glucagon, and some are antagonists for receptors, like the ghrelin receptor

Packer M, Zile MR, Kramer CM, et al Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity