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This study shows that targeted suppression of corticostriatal activity enhances cognitive flexibility and prevents weight loss in a rodent model of anorexia, implicating this circuit as a potential therapeutic target for core behavioural features of the disorder

It acts on three key hormone pathways: GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors

Thats a sign to reassess

Finally, when the treatment was interrupted, most, if not all, of the lost weight was regained [8]

Evaluation and Treatment of Adult Growth Hormone Deficiency: An Endocrine Society Clinical Practice Guideline
