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A decrease in LAV was observed in the HFrEF population (WMD: -5.4 ml [95% CI: -8.8, -2.0]

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Entre os efeitos indesejados mais comuns, esto distrbios gastrointestinais como nuseas, vmitos, diarreia ou at dores abdominais, frequentemente observados no incio do tratamento

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