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In February, NHS spending watchdog the National Institute for Health and Care Excellence (NICE) approved the weekly jab for obese patients with a weight-related illness, such as type 2 diabetes, or at high risk of a heart attack, as slimming down can help protect against these problems

While the test does not predict exact pain reliever response, it may illuminate why certain patients experience pronounced GI effects or inflammatory conditions that complicate pain management during GLP-1 therapy

Gut-Brain Axis GLP-1 Anti-Obesity Rx and Alcohol and Substance Use Disorders GLP-1 medications targeting the brain or gut may improve treatment of addictions

Report suspected side effects through the MHRA Yellow Card scheme and seek medical review if anxiety symptoms are severe, persistent, or accompanied by thoughts of self-harm

In others, it can be uncomfortable and significantly reduce appetite