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The occurrence of systemic reactions such as interstitial nephritis and Steven-Johnson syndrome have been reported in rare cases
47 Davis SR, Castelo-Branco C, Chedraui P, et al

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Based on STEP trial data, the median duration of a nausea episode is approximately 8 days

It has achieved -cell function preservation, meaningful reduction of albuminuria and significant improvements of several components of the MS [46, 47]
