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Summary: Combining Mounjaro and Adipex is not routinely recommended due to limited evidence and increased risk of adverse effects including cardiovascular strain and gastrointestinal disturbances
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The increased risk of amputation seen in the large, long-term Canagliflozin Cardiovascular Assessment Study (CANVAS) trial for canagliflozin, and select observational studies, merits further research but overall, there is currently no consistent evidence of SGLT2i exposure and increased risk of amputation

Reduced anxiety and depression, which are common comorbidities of obesity, may contribute to enhanced libido and sexual satisfaction

Reference O'Donnell, C., Ryan, O., Hogan, A
