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Over just a few weeks, she lost nearly 20 pounds, dropping to a dangerously low weight

We therefore carried out RNA-seq analysis using dissected intestines from the sterile glp-1(-) , fem-3(-) , and mog-3(-) mutant strains and compared to the WT

From 24.2% at 48 weeks to 28.7% at 68 weeks

Critically, 91% of participants maintained their weight loss through week 48 without significant regain, which addresses one of the most common concerns about obesity pharmacotherapy: whether results hold over time

If you are a hundred pounds overweight and youre extremely upset about it and youve given up all hope, I think GLP-1s can be not just this physical lifesaver, but this light at the end of a tunnel for you