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What are the primary concerns regarding GLP-1related anxiety

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Experimental models show that GLP-1 receptor activation inhibits NF-B signaling, thereby reducing transcription of pro-inflammatory mediators including IL-1, IL-6, and TNF-

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Int J Cancer

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Given that GLP-1-RAs alter gut motility and secretion, and that the gut microbiota can influence host eating behavior, including food preferences, it is plausible that these drugs indirectly influence taste perception by modulating microbial composition and the subsequent production of metabolites that can signal to the brain, potentially via vagal afferents or systemic circulation

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Staying hydrated and avoiding large meals can ease these symptoms

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