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A weak association exists between upper gastrointestinal symptoms and the rate of gastric emptying

Pharmacol Biochem Behav 2002;71:53354

TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice

In these contexts, it significantly affects nanoparticle delivery, targeting precision, controlled drug release, and overall therapeutic efficacy [504506]

GLP-1s reliably deliver weight loss - the open question is whether that pharmacologic "quiet" can be leveraged for durable behavior change during the window when change is easiest
