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In addition, associations between GLP-1R activation and coronary artery disease and parental mortality, a proxy for all-cause mortality, were investigated, as GLP-1RAs have been reported to reduce cardiovascular events and deaths

Maternal thyroid function at 11 to 13 weeks of gestation and subsequent fetal death

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[1] For weight management, tirzepatide is indicated for adults with a BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity, and must be used in conjunction with a reduced-calorie diet and increased physical activity

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