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In a substantial 72-week study involving 751 participants with obesity or overweight, Tirzepatide achieved an average weight loss of 20.2%, equating to approximately 50.3 pounds (22.8 kg)

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(4) Foundayo Eli Lilly's new obesity drug (FDA approved April 2026) may have different formulary status

[18] [19] Consider timing of meals to leverage the gastrocolic reflexeating stimulates colonic contractions, so consistent meal timing may promote regular bowel movements

Concurrent viral infections, including influenza or COVID-19, remain possible and should be considered in the differential diagnosis