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The STEP-HFpEF DM studies include individuals with obesity and heart failure, but also with DM2 [130]

48 , 49 , 50 There were no notable increases in the incidence of acute pancreatitis with semaglutide 2.4 mg

While GIP enhances insulin sensitivity and fat tissue effects, its interactions with the other receptor pathways remain incompletely understood
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Type I cells seem to have glia like function as they express several ion channels (inward rectifying K+ channel [ROMK], glutamate-aspartate transporter [GLAST], ENaC) which are supposed to clear ion currents [222335]
