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In late 2024, the Biden administration proposed Medicare coverage of anti-obesity medications, and in November 2025, Medicare announced it will begin covering weight-loss drugs like Wegovy and Mounjaro

However, this does not definitively exclude the possibility that some patients may experience back pain during therapy

metformin alone or vs

Notwithstanding these limitations, disproportionality analysis still remains a crucial tool for detecting potential safety signals associated with drugs and guiding further investigations [Reference Chen, Ding, Fu and Xiao16, Reference Zhou, Peng, Lin, Jiang, Peng and Gu29, Reference Blau, Tella, Taylor and Rother33, Reference Ding, Chen, Yang, Fang, Cao and Liu52]

Include electrolytes (sodium, potassium, magnesium) if you are eating significantly less than usual, as reduced food intake also means reduced electrolyte intake