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Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus

Before writing this review, we gathered the key details on how Pomegranate works and what it offers

Maccarrone M, Fiorucci L, Erba F, Bari M, Finazzi-Agr A, Ascoli F

2.1 Anti-inflammatory signaling and antioxidant effect Low-grade vascular inflammation is a central driver of atherogenesis, promoting monocyte recruitment, cytokine secretion, and plaque progression ( 2.2 Improvement of endothelial function and reduction of adhesion molecules Endothelial activation is an early biochemical event in atherosclerosis, characterized by increased expression of adhesion molecules, including Intercellular Adhesion Molecule 1 (ICAM-1), vascular Cell Adhesion Molecule 1 (VCAM-1), Monocyte Chemoattractant Protein-1 (MCP-1), and L-selectin