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Semaglutide users already experience reduced fluid intake due to appetite suppression, creating a compounding dehydration risk
Psychotropic medications, especially second-generation antipsychotics and some mood stabilizers, are well known for their metabolic side effects, including weight gain, insulin resistance, and dyslipidemia
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Several preclinical and animal studies have suggested that GLP-1RAs may have neurotrophic and neuroprotective effects, by reducing neuroinflammation, oxidative stress, apoptosis, and mitochondrial dysfunction and by promoting the growth and repair of neural cells, potentially enhancing cognitive functions [73,74,75]
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