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Participants The study included over 1.2 million T2DM patients who were prescribed anti-diabetic medications, including 181,795 prescribed GLP-1RAs between April 2013 and April 2019

Adults aged18 years with diabetes prescribed biguanides were included

GLP-1 receptor agonists and dual GLP-1/GIP co-agonists can produce substantial weight loss, but caloric restriction and weight loss trigger adaptive thermogenesis ...

DESCRIPTION: Retatrutide is an investigational peptide that activates three hormone receptors in the body namely the glucagon-like peptide-1 receptor the glucose-dependent insulinotropic peptide receptor and the glucagon receptor

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