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At the same time, transformation stories online often underplay the less glamorous realities: Muscle loss alongside fat loss Nutritional compromise from severely reduced intake Hair loss, fatigue, nausea, and GI adverse effects Weight regain after discontinuation Psychological pressure surrounding body image Unsupervised or socially influenced use Perhaps the most important point: these medications were never meant to replace lifestyle modification

Although dedicated trials of GLP-1RAs in AITD are lacking, preliminary reports suggest potential impacton thyroid volume, thyroid function, and autoimmune activity

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Patients facing high OOP costs often discontinue therapy prematurely or dose less frequently to stretch prescriptions