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Microbial metabolism and microbial cell death and turnover contribute to pools of microbial metabolites in the peripheral blood, where ~30% of all peripheral blood metabolites show associations with the GM and its genes [108, 109]

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Weight Loss Plateau on Semaglutide Semaglutide (Wegovy) produces an average of 14.9% body weight loss at 68 weeks on the 2.4mg maximum dose, per the STEP 1 trial (Wilding et al., NEJM 2021)
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