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Papakonstantinou, I., Tsioufis, K., & Katsi, V

Unlike other weight-loss medications, GLP-1s mimic a gut-based, appetite-modulating hormone that decreases blood sugar levels and sends signals of fullness to the brain

While lifestyle modifications can strengthen this response, many individuals benefit from prescription support to reach their weight loss and metabolic goals

An intermediate dose may be considered as the maintenance dose in fragile patients, thus minimizing risks associated with GI AEs

Eur J Neurosci 44:25692580 Jaramillo AA, Randall PA, Stewart S et al (2018a) Functional role for cortical-striatal circuitry in modulating alcohol self-administration