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The fusion product is resistant to DPP-4 degradation, due to an alanine to glycine substitution at position 2 (A2G) in each of the peptide sequences 28,29 , and has a plasma half-life of five days on average in humans 30,31,32

F., Calanna, S., Davies, M., Dicker, D., Garvey, W

Depression is a disorder characterized by a loss of interest in daily activities, fatigue, low mood, and cognitive symptoms that impair daily functioning [3]