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SGLT2 inhibitors are recommended for people with type 2 diabetes and chronic kidney disease to slow CKD progression and reduce albuminuria, benefits that extend beyond glucose lowering [106, 115, 116]

Identify patients with vagal involvement Track their symptom clusters Measure their response Separate them from other long-COVID phenotypes Without this, every study runs the risk of being written off before the true signal is even discovered

In this context, recent EULAR Points to Consider emphasize the importance of recognizing clinical and imaging features suggestive of progression from PsO to PsA, including arthralgia, enthesitis, subclinical synovitis on ultrasound or MRI, and elevated inflammatory markers (12)

Additionally, tirzepatide may delay gastric emptying, potentially reducing the absorption of oral medications including oral contraceptives

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