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GLP-1RA have been shown to affect various tissue organs, including the cardiovascular and urinary systems (Chen K

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In a systematic review, three-component Major Adverse Cardiovascular Events (3-p MACE) was reduced, with an HR of 0.86 (95% CI 0.800.92) for those over 65 years old, and there was an even more pronounced effect in those over age 75 (HR 0.75, 95% CI 0.610.92) (120)

Always coordinate any change with a prescriber