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(2007) Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

doi: 10.1038/s42255-021-00344-4

GLP-1s are glucagon-like peptide-1 (GLP-1) receptor agonists that mimic a naturally occurring hormone, making it easier to achieve and maintain a healthy weight

Ive worked with many individuals living with obesity who have experienced meaningful improvements in health, quality of life, blood sugar management, and cardiometabolic risk factors

Synaptic impairment is thought to occur early in the neurodegenerative process across a range of pathologies and may result from a complex combination of pathologic mechanisms including toxic amyloid beta and tau oligomers (Gutierrez and Limon, 2022
