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Have certain medical contraindications: GLP-1 medications should not be used by individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

By Payer Type, Private and Self-Pay Segment Accounts for 70% Market Share Private insurance and self-pay arrangements are projected to contribute 70% of the market in 2025, representing patients who access treatment through commercial health insurance or direct cash payment

So put that together with everything we just talked about with GLP ones, how they can help with caloric access

The mechanism is dose-dependent but not inevitable

[47] Steinert, R